Properly selected drugs for treating type 2 diabetes mellitus help to optimize the volume of sugar and avoid dangerous complications. Thanks to such medicines, it is possible to stimulate the production of insulin, slow the ingestion of glucose into the bloodstream, and, if necessary, increase the synthesis of insulin. The Diabetes Resource Coalition of Long Island has selected the best drugs for treating diabetes. Buying such preparations in online stores like My Canadian Pharmacy corp will not damage your budget since internet companies offer the lowest prices for diabetes products.
What are the most effective diabetes medications?
Actos ($0.75 per pill)
Actos is a European drug for lowering blood glucose levels, which is available in the form of tablets. The drug is used for treating diabetes mellitus type 2. This is the regulator of insulin with the main active substance pioglitazone. Actos reduces insulin resistance in the liver and peripheral tissues, thereby increasing the consumption of glucose and reducing its release from the liver. The action of pioglitazone does not promote the production of insulin by the pancreas.
Actos is manufactured in the form of tablets at a dosage of 15 mg and 30 mg. One packaging may contain a different number of tablets.
The usual dosage is 15 or 30 mg of pioglitazone per treatment. Depending on the individual condition of the patient, the doctor may decide to increase the dosage to a maximum of 45 mg. As a rule, the course of treatment with Actos is at least three months.
Glucotrol XL ($0.80 per pill)
Glucotrol XL is available in tablets of 5 mg and 10 mg. The drug is prescribed for type 2 diabetes if the diet has become ineffective or has not been effective at all. The medicine has contraindications. Their list, as usual, includes hypersensitivity to the components.
The drug is contraindicated in pregnant and breastfeeding women. With great caution, it is used in people who have renal or hepatic insufficiency. In patients with impaired function of the gastrointestinal tract, gastric paresis, intestinal obstruction and diarrhea may occur.
The dose of Glucotrol XL depends on the age of the patient, the severity of the disease and the concentration of glucose in the blood on an empty stomach. The medicine is taken orally. There are initial doses, which then can be increased to the maximum.
Amaryl is one of the most common anti-diabetic drugs belonging to the sulfonylurea group. Due to the active and additional components, the drug helps to lower the glucose concentration and effectively reduces the severity of the symptoms of diabetes mellitus. The antidiabetic drug is taken orally.
Amaryl is available in different dosages of 1 mg, 2 mg, 3 mg, 4 mg depending on the amount of active substance glimepiride which actively affects the release of insulin. Due to this component, the drug has a pancreatic effect.
The medication has an extrapancreatic effect – it improves the utilization of insulin with muscle and fat tissue. This occurs as a result of blocking the potassium channels in the cell membrane and increased intake of calcium into the cells. The extrapancreatic effect causes a decrease in immunity to insulin but also has an insignificant effect on the work of the heart and blood vessels.
The highest concentration of active substance is achieved with frequent use. For example, with the intake of 4 mg of glimepiride per day, the highest concentration is achieved in 2.5 hours. Complete absorption of the drug is achieved only with oral administration. The use of food slows down the effect of the preparation.
Janumet ($2.95 per pill)
Janumet is a drug for type 2 diabetes which can be used separately or in a combination of medications.
Janumet is an antidiabetic agent with two active ingredients so that taking one tablet can replace the need for several medications.
To date, combined medicines have a fairly high cost. But, according to medical experts, their effectiveness justifies such a price. My Canadian Pharmacy offers to buy Janumet at an affordable price.
The drug belongs to the group of preparations with hypoglycemic effect. That is why it is often prescribed for insulin-dependent diabetes mellitus.
Janumet tablets are available at a dosage of 50mg/500mg and are used in the following cases:
to reduce blood glucose, especially if dietary intake combined with moderate physical activity has shown a negative result;
if monotherapy with only one active ingredient did not bring the desired effect;
can be used as a complex therapy in conjunction with derivatives of sulphonylureas, insulin therapy or antagonists of PPAR-gamma.
With this medicine, it is possible to achieve suppression of excess glucagon, which, leads to the normalization of glucose in the blood.
Januvia ($4.80 per pill)
Januvia is a medication designed to lower blood sugar levels. The therapeutic effect of the drug is based on the active component sitagliptin, which promotes the deactivation of the enzyme DPP-4. The active substance regulates the metabolism of carbohydrates. The action of the medicine is based on the prevention of incretin destruction. Januvia is available at a dosage of 25 mg, 50 mg, 100 mg.
The use of the drug is recommended in the treatment of the second type of diabetes mellitus as a monotherapy and complex therapy. The tablets are recommended to be taken once a day, regardless of food intake. The instructions to Januvia warn against using the drug in a double dosage. People with pathologies of the kidneys and liver need to adjust the dosage of the drug in accordance with their condition.
Januvia is contraindicated in pregnancy and lactation, ketoacidosis (the accumulation of intermediate products of glucose metabolism in patients’ bodies), type 1 diabetes. With caution, the drug is used with hepatic and renal failure.
Reviews about Januvia are mainly positive, despite the fact that it does not belong to the powerful drugs. With timely treatment of the initial forms of diabetes mellitus, it is possible to achieve good results.
Important: All these drugs are selected individually, taking into account the course of the underlying disease and the presence of concomitant diseases.